structure of Resorufin b-D-cellobioside

Resorufin b-D-cellobioside

CAS No.: 1000404-48-7
M. Wt: 537.47
M. Fa: C24H27NO13
InChI Key: -

Names and Identifiers of Resorufin b-D-cellobioside

CAS Number

1000404-48-7

IUPAC Name

7-[(2S,3R,4R,5S,6R)-6-(hydroxymethyl)-5-[(2S,3R,4S,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3,4-bis(oxidanyl)oxan-2-yl]oxyphenoxazin-3-one

Canonical SMILES

C1=CC2=C(C=C1O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O)OC5=CC(=O)C=CC5=N2

Physical and chemical properties of Resorufin b-D-cellobioside

Molecular Formula

C24H27NO13

Molecular Weight

537.47

Water Solubility

Soluble in DMSO

Applications of Resorufin b-D-cellobioside

Resorufin beta-D-cellobioside is widely used in biochemical assays due to its fluorescent properties. Key applications include:

  • Enzyme assays: It serves as a substrate for measuring the activity of cellulases and other glycosidases.
  • Research on lysosomal storage disorders: The compound aids in studying enzyme deficiencies related to conditions like Pompe disease.
  • Diabetes research: It is utilized in exploring the kinetics of alpha-glucosidase inhibitors as potential therapeutic agents.

Interaction Studies of Resorufin b-D-cellobioside

Studies have shown that resorufin beta-D-cellobioside interacts with various enzymes, providing insights into their kinetic properties. For instance, it has been used to determine the kinetics of Clostridium cellulovorans endoglucanase, showcasing its role in understanding enzyme mechanisms and interactions within biochemical pathways. Additionally, its binding affinity to DNA under acidic conditions has been explored, revealing potential implications in molecular biology research.

Biological Activity of Resorufin b-D-cellobioside

Resorufin beta-D-cellobioside has shown significant biological activity as a substrate for various glycosidases, particularly cellulases. Its ability to produce a fluorescent signal upon enzymatic cleavage makes it valuable for studying enzyme kinetics and activity in biological samples. The compound has been utilized in research related to lysosomal storage disorders and diabetes, where enzymes like alpha-glucosidase are implicated.