N,N-Dimethylisopropylamine
CAS No.:
996-35-0
M. Wt:
87.163
M. Fa:
C5H13N
InChI Key:
VMOWKUTXPNPTEN-UHFFFAOYSA-N
Appearance:
Colorless Liquid
Names and Identifiers of N,N-Dimethylisopropylamine
CAS Number |
996-35-0 |
|---|---|
EC Number |
213-635-5 |
IUPAC Name |
N,N-dimethylpropan-2-amine |
InChI |
InChI=1S/C5H13N/c1-5(2)6(3)4/h5H,1-4H3 |
InChIKey |
VMOWKUTXPNPTEN-UHFFFAOYSA-N |
Canonical SMILES |
CC(C)N(C)C |
UNII |
WA4TE070J7 |
Physical and chemical properties of N,N-Dimethylisopropylamine
Acidity coefficient |
9.91±0.50(Predicted) |
|---|---|
Boiling Point |
65.8±0.0 °C at 760 mmHg |
BRN |
1696929 |
Density |
0.7±0.1 g/cm3 |
Exact Mass |
87.104797 |
explosive limit |
1.0-8.1%(V) |
Flash Point |
-9.4±0.0 °C |
Index of Refraction |
1.402 |
LogP |
0.94 |
Melting Point |
-115.88°C (estimate) |
Molecular Formula |
C5H13N |
Molecular Weight |
87.163 |
pH |
11.5 (100g/l, H2O, 20℃) |
PSA |
3.24000 |
Stability |
Stable. Highly flammable. Incompatible with strong oxidizing agents. |
Storage condition |
Store below +30°C. |
Vapour Pressure |
155.5±0.1 mmHg at 25°C |
Water Solubility |
100g/L at 25℃ |
Safety Information of N,N-Dimethylisopropylamine
Applications of N,N-Dimethylisopropylamine
N,N-Dimethylisopropylamine finds applications across various fields:
- Organic Synthesis: It is widely used as a base in organic synthesis due to its ability to stabilize reaction intermediates without participating as a nucleophile.
- Pharmaceutical Industry: The compound may be involved in synthesizing pharmaceutical intermediates or active pharmaceutical ingredients.
- Chemical Research: It serves as a reagent in research settings for studying reaction mechanisms involving nitrogen-containing compounds.
Interaction Studies of N,N-Dimethylisopropylamine
Research has explored the interaction dynamics of N,N-dimethylisopropylamine with other compounds:
- Methyl Migration Studies: Investigations into methyl migration between protonated forms of N,N-dimethylisopropylamine and other aliphatic amines have provided insights into its reactivity and behavior under different conditions.
- Fragmentation Dynamics: Studies on energy flow and fragmentation upon excitation have enhanced understanding of its electronic properties and potential applications in material science.
Biological Activity of N,N-Dimethylisopropylamine
While specific biological activities of N,N-dimethylisopropylamine are less documented compared to other compounds, it is known to exhibit irritant properties and can be toxic upon exposure. Its acute toxicity and corrosive nature necessitate careful handling in laboratory settings. Studies have shown that it can participate in methylation processes involving nitrogen-containing compounds, indicating potential interactions with biological systems.
Physical sample testing spectrum (NMR) of N,N-Dimethylisopropylamine



