8-bromo-7-fluoro-2-methoxyquinoline
CAS No.:
1001322-87-7
M. Wt:
256.07100
M. Fa:
C10H7BrFNO
InChI Key:
-
Names and Identifiers of 8-bromo-7-fluoro-2-methoxyquinoline
CAS Number |
1001322-87-7 |
|---|---|
IUPAC Name |
8-bromanyl-7-fluoranyl-2-methoxy-quinoline |
Canonical SMILES |
COC1=NC2=C(C=CC(=C2Br)F)C=C1 |
Physical and chemical properties of 8-bromo-7-fluoro-2-methoxyquinoline
Exact Mass |
254.97000 |
|---|---|
LogP |
3.14500 |
Molecular Formula |
C10H7BrFNO |
Molecular Weight |
256.07100 |
PSA |
22.12000 |
Storage condition |
2-8°C |
Applications of 8-bromo-7-fluoro-2-methoxyquinoline
The compound's unique properties make it suitable for various applications:
- Pharmaceutical Development: Its biological activities make it a candidate for drug discovery, particularly in antimicrobial and anticancer therapies.
- Chemical Research: Used as a building block in organic synthesis for creating more complex heterocycles.
Interaction Studies of 8-bromo-7-fluoro-2-methoxyquinoline
Interaction studies have focused on how 8-bromo-7-fluoro-2-methoxyquinoline interacts with biological targets:
- Enzyme Inhibition: Research indicates potential interactions with enzymes involved in metabolic pathways, suggesting avenues for therapeutic applications.
- DNA Binding Studies: The compound has been investigated for its ability to bind to DNA, which may contribute to its anticancer properties
Biological Activity of 8-bromo-7-fluoro-2-methoxyquinoline
8-Bromo-7-fluoro-2-methoxyquinoline exhibits notable biological activities. Studies indicate that it possesses:
- Antimicrobial Properties: It has shown effectiveness against various bacterial strains.
- Anticancer Activity: The compound has been evaluated for its potential in inhibiting cancer cell proliferation, making it a candidate for further drug development