structure of 7-Hydroxy-2',5,8-trimethoxyflavanone

7-Hydroxy-2',5,8-trimethoxyflavanone

CAS No.: 100079-34-3
M. Wt: 330.33
M. Fa: C18H18O6
InChI Key: FEIYIVGWSITXPN-AWEZNQCLSA-N

Names and Identifiers of 7-Hydroxy-2',5,8-trimethoxyflavanone

CAS Number

100079-34-3

IUPAC Name

(2S)-7-hydroxy-5,8-dimethoxy-2-(2-methoxyphenyl)-2,3-dihydrochromen-4-one

InChI

InChI=1S/C18H18O6/c1-21-13-7-5-4-6-10(13)14-8-11(19)16-15(22-2)9-12(20)17(23-3)18(16)24-14/h4-7,9,14,20H,8H2,1-3H3/t14-/m0/s1

InChIKey

FEIYIVGWSITXPN-AWEZNQCLSA-N

Canonical SMILES

COC1=CC=CC=C1C2CC(=O)C3=C(C=C(C(=C3O2)OC)O)OC

Isomeric SMILES

COC1=CC=CC=C1[C@@H]2CC(=O)C3=C(C=C(C(=C3O2)OC)O)OC

Physical and chemical properties of 7-Hydroxy-2',5,8-trimethoxyflavanone

Boiling Point

552.9±50.0 °C at 760 mmHg

Density

1.3±0.1 g/cm3

Exact Mass

330.110352

Flash Point

202.8±23.6 °C

Index of Refraction

1.584

LogP

3.55

Molecular Formula

C18H18O6

Molecular Weight

330.33

PSA

74.22000

Storage condition

2-8°C

Vapour Pressure

0.0±1.5 mmHg at 25°C

Interaction Studies of 7-Hydroxy-2',5,8-trimethoxyflavanone

Research on the interactions of 7-hydroxy-2',5,8-trimethoxyflavanone with other compounds has revealed insights into its synergistic effects. Interaction studies typically focus on:

  • Drug Synergy: Investigating how this flavonoid enhances or modifies the effects of conventional drugs.
  • Metabolic Pathways: Understanding how it interacts with metabolic enzymes can help predict its pharmacokinetics and potential side effects.

Biological Activity of 7-Hydroxy-2',5,8-trimethoxyflavanone

7-Hydroxy-2',5,8-trimethoxyflavanone exhibits a range of biological activities that are typical for flavonoids. These include:

  • Antioxidant Properties: It has been shown to scavenge free radicals, thereby protecting cells from oxidative stress.
  • Anti-inflammatory Effects: The compound may inhibit inflammatory pathways, making it a candidate for treating inflammatory diseases.
  • Antimicrobial Activity: Preliminary studies suggest that it possesses antimicrobial properties against certain pathogens.