structure of 7-Chloro-4-fluoro-3-iodo-1H-indazole

7-Chloro-4-fluoro-3-iodo-1H-indazole

CAS No.: 1000342-09-5
M. Wt: 296.468
M. Fa: C7H3ClFIN2
InChI Key: QHODPGTVJUGODH-UHFFFAOYSA-N

Names and Identifiers of 7-Chloro-4-fluoro-3-iodo-1H-indazole

CAS Number

1000342-09-5

IUPAC Name

7-chloro-4-fluoro-3-iodo-2H-indazole

InChI

InChI=1S/C7H3ClFIN2/c8-3-1-2-4(9)5-6(3)11-12-7(5)10/h1-2H,(H,11,12)

InChIKey

QHODPGTVJUGODH-UHFFFAOYSA-N

Canonical SMILES

C1=C(C2=C(NN=C2C(=C1)Cl)I)F

Physical and chemical properties of 7-Chloro-4-fluoro-3-iodo-1H-indazole

Boiling Point

393.1±37.0 °C at 760 mmHg

Density

2.2±0.1 g/cm3

Exact Mass

295.901337

Flash Point

191.6±26.5 °C

Index of Refraction

1.752

LogP

3.75

Molecular Formula

C7H3ClFIN2

Molecular Weight

296.468

PSA

28.68000

Vapour Pressure

0.0±0.9 mmHg at 25°C

Applications of 7-Chloro-4-fluoro-3-iodo-1H-indazole

The applications of 7-chloro-4-fluoro-3-iodo-1H-indazole extend across various fields:

  • Pharmaceutical Development: Its structural features make it a candidate for drug development targeting various diseases.
  • Material Science: The compound may also find applications in developing new materials due to its unique electronic properties.

Interaction Studies of 7-Chloro-4-fluoro-3-iodo-1H-indazole

Studies focusing on the interactions of 7-chloro-4-fluoro-3-iodo-1H-indazole with biological targets are crucial for understanding its mechanism of action. Key areas include:

  • Protein Binding Studies: Understanding how this compound interacts with proteins can provide insights into its biological activity.
  • Receptor Binding Assays: Evaluating binding affinities to specific receptors can help identify potential therapeutic uses.

Biological Activity of 7-Chloro-4-fluoro-3-iodo-1H-indazole

Indazole derivatives, including 7-chloro-4-fluoro-3-iodo-1H-indazole, have been studied for their potential pharmacological activities. Research indicates that such compounds may exhibit:

  • Anticancer Properties: Some indazole derivatives have shown promise in inhibiting cancer cell proliferation.
  • Antimicrobial Activity: There are indications that these compounds may possess antibacterial and antifungal properties.
  • Neuroprotective Effects: Certain studies suggest potential benefits in neurodegenerative disease models.