4-Fluoro-1-methoxy-2-naphthoic acid
Names and Identifiers of 4-Fluoro-1-methoxy-2-naphthoic acid
CAS Number |
1000386-63-9 |
|---|---|
IUPAC Name |
4-fluoranyl-1-methoxy-naphthalene-2-carboxylic acid |
Canonical SMILES |
COC1=C(C=C(C2=CC=CC=C21)F)C(=O)O |
Physical and chemical properties of 4-Fluoro-1-methoxy-2-naphthoic acid
Exact Mass |
220.05400 |
|---|---|
LogP |
2.68570 |
Molecular Formula |
C12H9FO3 |
Molecular Weight |
220.19600 |
PSA |
46.53000 |
Applications of 4-Fluoro-1-methoxy-2-naphthoic acid
4-Fluoro-1-methoxy-2-naphthoic acid has potential applications in various fields:
- Pharmaceuticals: Due to its biological activity, it may serve as a lead compound in drug discovery for anti-inflammatory or analgesic medications.
- Organic Synthesis: Its ability to undergo nucleophilic substitution makes it useful in synthesizing more complex organic molecules.
- Materials Science: The unique properties of fluorinated compounds can be exploited in developing advanced materials with specific characteristics.
Interaction Studies of 4-Fluoro-1-methoxy-2-naphthoic acid
Interaction studies involving 4-fluoro-1-methoxy-2-naphthoic acid focus on its reactivity with biological targets and other chemical entities. These studies often reveal how substituents affect binding affinity and selectivity towards enzymes or receptors, thereby influencing its pharmacological profile. Computational studies have shown that substituent effects play a critical role in determining the reactivity and biological activities of naphthoic acids.
Biological Activity of 4-Fluoro-1-methoxy-2-naphthoic acid
The biological activity of 4-fluoro-1-methoxy-2-naphthoic acid has been studied in various contexts. Substituents on naphthoic acids significantly influence their pharmacological properties. For instance, fluorinated compounds often exhibit enhanced metabolic stability and bioavailability compared to their non-fluorinated counterparts. Research indicates that such compounds may possess anti-inflammatory and analgesic properties, making them candidates for drug development.