structure of 4-AMINO-6-ISOPROPYL (1H)INDAZOLE

4-AMINO-6-ISOPROPYL (1H)INDAZOLE

CAS No.: 1000343-74-7
M. Wt: 175.230
M. Fa: C10H13N3
InChI Key: -

Names and Identifiers of 4-AMINO-6-ISOPROPYL (1H)INDAZOLE

CAS Number

1000343-74-7

IUPAC Name

6-propan-2-yl-1H-indazol-4-amine

Canonical SMILES

CC(C)C1=CC(=C2C=NNC2=C1)N

Physical and chemical properties of 4-AMINO-6-ISOPROPYL (1H)INDAZOLE

Boiling Point

371.3±22.0 °C at 760 mmHg

Density

1.2±0.1 g/cm3

Exact Mass

175.110947

Flash Point

206.1±9.5 °C

Index of Refraction

1.669

LogP

1.88

Molecular Formula

C10H13N3

Molecular Weight

175.230

PSA

54.70000

Vapour Pressure

0.0±0.8 mmHg at 25°C

Interaction Studies of 4-AMINO-6-ISOPROPYL (1H)INDAZOLE

Interaction studies focus on how 6-(Propan-2-yl)-1H-indazol-4-amine interacts with biological targets:

  • Protein Binding Studies: Investigating how well the compound binds to specific proteins involved in disease pathways.
  • Enzyme Inhibition Assays: Evaluating the ability of the compound to inhibit enzymes linked to cancer progression or microbial resistance.

These studies are crucial for understanding the pharmacodynamics and pharmacokinetics of the compound.

Biological Activity of 4-AMINO-6-ISOPROPYL (1H)INDAZOLE

Research indicates that 6-(Propan-2-yl)-1H-indazol-4-amine exhibits several biological activities:

  • Antitumor Activity: Similar indazole derivatives have been shown to inhibit cancer cell proliferation, suggesting potential use in oncology.
  • Antimicrobial Properties: Compounds related to this structure demonstrate activity against various bacterial and fungal strains.
  • Anti-inflammatory Effects: Some studies indicate that derivatives may possess anti-inflammatory properties, potentially useful in treating inflammatory diseases.