structure of 4-(2-Chlorophenyl)piperidine

4-(2-Chlorophenyl)piperidine

CAS No.: 100129-35-9
M. Wt: 195.68900
M. Fa: C11H14ClN
InChI Key: LIQZVQFEBKPDRL-UHFFFAOYSA-N
Appearance: Pale-yellow Semi-Solid

Names and Identifiers of 4-(2-Chlorophenyl)piperidine

CAS Number

100129-35-9

MDL Number

MFCD09026406

IUPAC Name

4-(2-chlorophenyl)piperidine

InChI

InChI=1S/C11H14ClN/c12-11-4-2-1-3-10(11)9-5-7-13-8-6-9/h1-4,9,13H,5-8H2

InChIKey

LIQZVQFEBKPDRL-UHFFFAOYSA-N

Canonical SMILES

C1CNCCC1C2=CC=CC=C2Cl

UNSPSC Code

12352100

Physical and chemical properties of 4-(2-Chlorophenyl)piperidine

Acidity coefficient

10.09±0.10(Predicted)

Boiling Point

276.3°C

Density

1.095±0.06 g/cm3(Predicted)

Exact Mass

195.08100

LogP

3.13580

Molecular Formula

C11H14ClN

Molecular Weight

195.68900

PSA

12.03000

Storage condition

2-8°C

Safety Information of 4-(2-Chlorophenyl)piperidine

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 4-(2-Chlorophenyl)piperidine

4-(2-Chlorophenyl)piperidine is primarily used in medicinal chemistry for:

  • Drug Development: Its structural characteristics make it a valuable scaffold for designing new pharmaceuticals, particularly those targeting neurological and psychiatric disorders.
  • Antimicrobial Agents: Due to its biological activity, it is being explored for potential use as an antimicrobial agent.

Interaction Studies of 4-(2-Chlorophenyl)piperidine

Interaction studies involving 4-(2-Chlorophenyl)piperidine have focused on its role as an enzyme inhibitor. Specifically, its inhibition of cytochrome P450 enzymes, particularly CYP2D6, has implications for drug-drug interactions and personalized medicine approaches. Understanding these interactions is crucial for predicting metabolic pathways and optimizing therapeutic regimens involving this compound.

Biological Activity of 4-(2-Chlorophenyl)piperidine

Research indicates that 4-(2-Chlorophenyl)piperidine exhibits significant biological activities, particularly as an inhibitor of certain enzymes. Notably, it has been identified as a CYP2D6 inhibitor, which is crucial for drug metabolism in humans. Additionally, studies have shown that derivatives of piperidine compounds often possess antimicrobial properties, suggesting potential applications in treating infections.