3-Methoxy-2-nitrobenzamide
Names and Identifiers of 3-Methoxy-2-nitrobenzamide
CAS Number |
99595-85-4 |
|---|---|
IUPAC Name |
3-methoxy-2-nitrobenzamide |
InChI |
InChI=1S/C8H8N2O4/c1-14-6-4-2-3-5(8(9)11)7(6)10(12)13/h2-4H,1H3,(H2,9,11) |
InChIKey |
MZGJDLQJIXSZRB-UHFFFAOYSA-N |
Canonical SMILES |
COC1=CC=CC(=C1[N+](=O)[O-])C(=O)N |
UNSPSC Code |
12352100 |
Physical and chemical properties of 3-Methoxy-2-nitrobenzamide
Boiling Point |
321.5ºC at 760 mmHg |
|---|---|
Density |
1.362g/cm3 |
Exact Mass |
196.04800 |
Flash Point |
148.2ºC |
H Bond Acceptors |
4 |
H Bond Donors |
1 |
Index of Refraction |
1.587 |
LogP |
1.92580 |
Molecular Formula |
C8H8N2O4 |
Molecular Weight |
196.16000 |
PSA |
98.14000 |
Storage condition |
2-8℃ |
Safety Information of 3-Methoxy-2-nitrobenzamide
Applications of 3-Methoxy-2-nitrobenzamide
3-Methoxy-2-nitrobenzamide has several applications:
- Pharmaceuticals: Its antimicrobial properties make it a candidate for developing new antibiotics.
- Chemical Research: Used as an intermediate in synthesizing other organic compounds.
- Agricultural Chemistry: Potential use in developing agrochemicals due to its biological activity.
The versatility of this compound allows it to be explored across multiple fields.
Interaction Studies of 3-Methoxy-2-nitrobenzamide
Interaction studies involving 3-Methoxy-2-nitrobenzamide focus on its binding affinity to various biological targets, particularly enzymes and receptors related to microbial resistance. These studies are crucial for understanding its mechanism of action and potential side effects when used therapeutically. Preliminary data suggest that it may interact with bacterial enzymes, inhibiting their function and leading to cell death.
Biological Activity of 3-Methoxy-2-nitrobenzamide
Research indicates that 3-Methoxy-2-nitrobenzamide exhibits antimicrobial properties. Studies have shown that substituted benzamides, including this compound, demonstrate activity against both Gram-positive and Gram-negative bacteria. The presence of the nitro group is often associated with enhanced antimicrobial efficacy, making it a candidate for further exploration in drug development.
Physical sample testing spectrum (NMR) of 3-Methoxy-2-nitrobenzamide
Cas:4920-80-3
Cas:15865-57-3