structure of 2-Fluoro-6-(pyrrolidin-1-yl)pyridine

2-Fluoro-6-(pyrrolidin-1-yl)pyridine

CAS No.: 1000981-50-9
M. Wt: 166.19500
M. Fa: C9H11FN2
InChI Key: DITJTHCVPDLQAT-UHFFFAOYSA-N

Names and Identifiers of 2-Fluoro-6-(pyrrolidin-1-yl)pyridine

CAS Number

1000981-50-9

MDL Number

MFCD10699460

IUPAC Name

2-fluoro-6-pyrrolidin-1-ylpyridine

InChI

InChI=1S/C9H11FN2/c10-8-4-3-5-9(11-8)12-6-1-2-7-12/h3-5H,1-2,6-7H2

InChIKey

DITJTHCVPDLQAT-UHFFFAOYSA-N

Canonical SMILES

C1CCN(C1)C2=NC(=CC=C2)F

UNSPSC Code

12352100

Physical and chemical properties of 2-Fluoro-6-(pyrrolidin-1-yl)pyridine

Exact Mass

166.09100

H Bond Acceptors

2

H Bond Donors

0

LogP

1.88590

Molecular Formula

C9H11FN2

Molecular Weight

166.19500

PSA

16.13000

Safety Information of 2-Fluoro-6-(pyrrolidin-1-yl)pyridine

Pictograms

Signal Word

Warning

Safety Data Sheet

Supports customized editing of SDS information and downloading in PDF documents.

Applications of 2-Fluoro-6-(pyrrolidin-1-yl)pyridine

The applications of 2-Fluoro-6-(pyrrolidin-1-yl)pyridine span several fields:

  • Medicinal Chemistry: It serves as a building block for synthesizing pharmaceutical compounds targeting neurological disorders.
  • Material Science: The compound is explored for its potential use in developing organic electronic materials due to its unique electronic properties.
  • Biochemical Research: It is utilized as a probe in biochemical assays to study enzyme interactions and receptor binding dynamics.

Interaction Studies of 2-Fluoro-6-(pyrrolidin-1-yl)pyridine

Interaction studies focus on understanding how 2-Fluoro-6-(pyrrolidin-1-yl)pyridine interacts with various biological targets:

  • Receptor Binding: Investigations into its affinity for nicotinic acetylcholine receptors have been prominent, given its structural similarities to nicotine.
  • Enzyme Modulation: Studies assess how this compound influences enzyme activity, potentially affecting metabolic pathways related to neurotransmission.

These studies are vital for elucidating its therapeutic potential and mechanism of action.

Biological Activity of 2-Fluoro-6-(pyrrolidin-1-yl)pyridine

Research indicates that 2-Fluoro-6-(pyrrolidin-1-yl)pyridine exhibits significant biological activity, particularly in neuroscience and pharmacology. It has been investigated for its potential as:

  • Neuroprotective Agent: Due to its structural similarity to nicotine, it may interact with nicotinic acetylcholine receptors, suggesting potential applications in treating neurodegenerative diseases.
  • Modulator of Enzyme Activity: The compound's ability to bind to specific enzymes may influence various biochemical pathways, making it a valuable tool in drug discovery.

Retrosynthesis analysis of 2-Fluoro-6-(pyrrolidin-1-yl)pyridine

  • Route#1

    Cas:123-75-1
    Cas:1513-65-1
    Cas:1000981-50-9