2,4-Dichloropyrrolo[2,1-f][1,2,4]triazine-7-carbaldehyde

The applications of 2,4-Dichloropyrrolo[2,1-f][1,2,4]triazine-7-carbaldehyde span various fields:

• Pharmaceuticals: Its potential as a kinase inhibitor positions it as a candidate for cancer therapy.
• Material Science: Due to its unique electronic properties, it may find applications in developing organic semiconductors or dyes.
• Agriculture: Compounds with similar structures have been explored for use as herbicides or fungicides .

Interaction studies involving 2,4-Dichloropyrrolo[2,1-f][1,2,4]triazine-7-carbaldehyde focus on its binding affinity to various biological targets. Preliminary studies suggest that it may exhibit interactions with key enzymes involved in cell signaling pathways relevant to cancer progression. Molecular docking studies can provide insights into its binding modes and affinities for specific kinases .

Research indicates that compounds containing the pyrrolo[2,1-f][1,2,4]triazine scaffold exhibit significant biological activities, particularly as kinase inhibitors. For instance, derivatives of this compound have shown potential in targeting vascular endothelial growth factor receptor 2 and epidermal growth factor receptor kinases. The unique structure of 2,4-Dichloropyrrolo[2,1-f][1,2,4]triazine-7-carbaldehyde may enhance its potency and selectivity against specific cancer-related targets .