![structure of 2-(2-bromoethyl)-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one](https://molwiki.oss-cn-hongkong.aliyuncs.com/structure/43/1000932-43-3.svg)
2-(2-bromoethyl)-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one
CAS No.:
1000932-43-3
M. Wt:
242.07
M. Fa:
C8H8BrN3O
InChI Key:
-
Appearance:
Solid
Names and Identifiers of 1000932-43-3
CAS Number |
1000932-43-3 |
|---|---|
IUPAC Name |
2-(2-bromoethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-one |
Canonical SMILES |
C1=CC2=NN(C(=O)N2C=C1)CCBr |
Physical and chemical properties of 1000932-43-3
Acidity coefficient |
0.49±0.20(Predicted) |
|---|---|
Boiling Point |
309.4±44.0 °C(Predicted) |
Density |
1.72±0.1 g/cm3(Predicted) |
Molecular Formula |
C8H8BrN3O |
Molecular Weight |
242.07 |
Safety Information of 1000932-43-3
Applications of 1000932-43-3
The compound has several applications across different fields:
- Pharmaceuticals: It serves as a lead compound for developing new drugs targeting specific biological pathways.
- Material Science: Its unique structure allows for potential use in creating novel materials with specific properties.
- Research Tools: It is utilized in proteomics and other biochemical research due to its reactivity and ability to modify biomolecules .
Interaction Studies of 1000932-43-3
Studies on interaction mechanisms involving 2-(2-bromoethyl)-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one suggest:
- Protein Binding: Investigations into how this compound interacts with proteins can reveal insights into its biological mechanisms.
- Receptor Interaction: Its role as a modulator for receptors like P2X7 suggests significant implications for drug development targeting pain and inflammation .
Biological Activity of 1000932-43-3
Research indicates that compounds similar to 2-(2-bromoethyl)-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one exhibit various biological activities:
- Antimicrobial Properties: Some derivatives have shown effectiveness against bacterial strains.
- Anticancer Activity: Compounds in this class are being studied for their potential in cancer therapy due to their ability to inhibit tumor growth.
- P2X7 Modulation: Related compounds have been identified as modulators of the P2X7 receptor, which is implicated in neuroinflammation and pain pathways .