structure of ethyl 2-(4-chloroquinazolin-7-yl)oxyacetate

ethyl 2-(4-chloroquinazolin-7-yl)oxyacetate

CAS No.: 1000577-87-6
M. Wt: 266.680
M. Fa: C12H11ClN2O3
InChI Key: UGGIDCDRRBNSNV-UHFFFAOYSA-N

Names and Identifiers of 1000577-87-6

CAS Number

1000577-87-6

MDL Number

MFCD09878676

IUPAC Name

ethyl 2-[(4-chloroquinazolin-7-yl)oxy]acetate

InChI

InChI=1S/C12H11ClN2O3/c1-2-17-11(16)6-18-8-3-4-9-10(5-8)14-7-15-12(9)13/h3-5,7H,2,6H2,1H3

InChIKey

UGGIDCDRRBNSNV-UHFFFAOYSA-N

Canonical SMILES

CCOC(=O)COC1=CC=C2C(=C1)N=CN=C2Cl

UNSPSC Code

12352100

Physical and chemical properties of 1000577-87-6

Boiling Point

398.7±27.0 °C at 760 mmHg

Density

1.3±0.1 g/cm3

Exact Mass

266.045807

Flash Point

194.9±23.7 °C

H Bond Acceptors

4

H Bond Donors

0

Index of Refraction

1.594

LogP

1.40

Molecular Formula

C12H11ClN2O3

Molecular Weight

266.680

Vapour Pressure

0.0±0.9 mmHg at 25°C

Safety Information of 1000577-87-6

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 1000577-87-6

Ethyl 2-((4-chloroquinazolin-7-yl)oxy)acetate has potential applications in pharmaceutical development due to its biological activity. It may serve as a lead compound for designing new drugs targeting specific diseases, particularly those related to cancer or metabolic disorders. Additionally, it can be used as an intermediate in synthesizing more complex organic molecules.

Interaction Studies of 1000577-87-6

Interaction studies involving ethyl 2-((4-chloroquinazolin-7-yl)oxy)acetate primarily focus on its binding affinity to various biological targets, including enzymes and receptors associated with disease pathways. These studies are crucial for understanding the mechanism of action of this compound and its derivatives in therapeutic contexts.

Biological Activity of 1000577-87-6

Quinazoline derivatives are known for their biological activities, including anti-cancer, anti-inflammatory, and antimicrobial effects. Ethyl 2-((4-chloroquinazolin-7-yl)oxy)acetate has been investigated for its potential to inhibit certain enzymes involved in cancer proliferation. Studies suggest that compounds containing quinazoline moieties may enhance high-density lipoprotein cholesterol levels, indicating a possible role in cardiovascular health.