structure of Hexahydropyrrolo[1,2-a]pyrazin-4(1H)-one

Hexahydropyrrolo[1,2-a]pyrazin-4(1H)-one

CAS No.: 1000577-63-8
M. Wt: 140.183
M. Fa: C7H12N2O
InChI Key: HAAZJWVQKLGNDT-UHFFFAOYSA-N
Appearance: Colorless Liquid

Names and Identifiers of 1000577-63-8

CAS Number

1000577-63-8

EC Number

837-079-3

IUPAC Name

2,3,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-4-one

InChI

InChI=1S/C7H12N2O/c10-7-5-8-4-6-2-1-3-9(6)7/h6,8H,1-5H2

InChIKey

HAAZJWVQKLGNDT-UHFFFAOYSA-N

Canonical SMILES

C1CC2CNCC(=O)N2C1

Physical and chemical properties of 1000577-63-8

Boiling Point

284.4±29.0 °C at 760 mmHg

Density

1.2±0.1 g/cm3

Exact Mass

140.094955

Flash Point

125.8±24.3 °C

Index of Refraction

1.551

LogP

-1.13

Molecular Formula

C7H12N2O

Molecular Weight

140.183

PSA

32.34000

Vapour Pressure

0.0±0.6 mmHg at 25°C

Safety Information of 1000577-63-8

Pictograms

Signal Word

 Danger

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 1000577-63-8

Hexahydropyrrolo[1,2-a]pyrazin-4(1H)-one and its derivatives have several applications, particularly in medicinal chemistry:

  • Drug Development: Due to its biological activity, it serves as a lead compound for developing new pharmaceuticals targeting various diseases.
  • Chemical Probes: Its unique structure makes it suitable for use as a chemical probe in biological studies.
  • Synthetic Intermediates: It acts as an intermediate in the synthesis of more complex organic molecules used in research and industry.

Interaction Studies of 1000577-63-8

Interaction studies involving hexahydropyrrolo[1,2-a]pyrazin-4(1H)-one focus on its binding affinities with various biological targets:

  • Receptor Binding Studies: Investigations into how this compound interacts with specific receptors can help elucidate its mechanism of action and therapeutic potential.
  • Enzyme Inhibition Studies: Research has indicated that certain derivatives may act as inhibitors for specific enzymes involved in disease pathways, providing insights into their pharmacological profiles.

Biological Activity of 1000577-63-8

Research indicates that hexahydropyrrolo[1,2-a]pyrazin-4(1H)-one exhibits various biological activities. Its derivatives have shown promise as:

  • Antimicrobial Agents: Some studies suggest that compounds derived from hexahydropyrrolo[1,2-a]pyrazin-4(1H)-one possess antimicrobial properties, making them candidates for further development as antibiotics.
  • Anticancer Activity: Certain derivatives have demonstrated cytotoxic effects against cancer cell lines, indicating potential as anticancer agents.
  • Neuroprotective Effects: There is emerging evidence of neuroprotective properties, which could be beneficial in treating neurodegenerative diseases.