structure of 1,4-Piperazinediethanesulfonic acid, sodium salt (2:3)

1,4-Piperazinediethanesulfonic acid, sodium salt (2:3)

CAS No.: 100037-69-2
M. Wt: 336.86
M. Fa: C8H18N2NaO6S2
InChI Key: FPDACHMSOMILQI-UHFFFAOYSA-K
Appearance: White Solid

Names and Identifiers of 100037-69-2

CAS Number

100037-69-2

EC Number

600-018-4

IUPAC Name

trisodium;2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonate;2-[4-(2-sulfonatoethyl)piperazin-1-yl]ethanesulfonate

InChI

InChI=1S/2C8H18N2O6S2.3Na/c2*11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16;;;/h2*1-8H2,(H,11,12,13)(H,14,15,16);;;/q;;3*+1/p-3

InChIKey

FPDACHMSOMILQI-UHFFFAOYSA-K

Canonical SMILES

C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)[O-].C1CN(CCN1CCS(=O)(=O)[O-])CCS(=O)(=O)[O-].[Na+].[Na+].[Na+]

Physical and chemical properties of 100037-69-2

Acidity coefficient

6.8(at 25℃)

Exact Mass

670.067078

Melting Point

300 °C

Molecular Formula

C8H18N2NaO6S2

Molecular Weight

336.86

pH Range

6.1 - 7.5

PSA

272.45000

Solubility

H2O: 0.5 g/mL, clear, colorless

Storage condition

Store at RT.

Water Solubility

soluble

Applications of 100037-69-2

Trisodium 2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonate finds numerous applications in:

  • Biochemical Research: Used as a buffering agent in various assays and experiments.
  • Cell Culture: Maintains optimal pH conditions for cell growth and viability.
  • Pharmaceutical Development: Acts as an excipient in drug formulations to stabilize active ingredients.

Its unique properties make it indispensable in many laboratory settings .

Interaction Studies of 100037-69-2

Studies on the interactions of trisodium 2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonate with biomolecules have shown that it can effectively stabilize protein structures during purification processes. Its zwitterionic nature minimizes non-specific binding, enhancing the purity of isolated proteins. Additionally, interaction studies have demonstrated its compatibility with various enzymes, maintaining their activity across a range of pH levels .

Biological Activity of 100037-69-2

The biological activity of trisodium 2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonate is primarily attributed to its buffering capacity. It maintains the pH stability required for enzyme activity and cellular processes. Additionally, it has been shown to have minimal toxicity, making it suitable for use in cell culture and other biological assays. Its zwitterionic nature allows it to interact effectively with biomolecules without interfering with their function .