structure of 3-Iodo-4-methyl-1H-pyrrolo[3,2-c]pyridine

3-Iodo-4-methyl-1H-pyrrolo[3,2-c]pyridine

CAS No.: 1000342-66-4
M. Wt: 258.059
M. Fa: C8H7IN2
InChI Key: AUDKTNCLJDKEJL-UHFFFAOYSA-N

Names and Identifiers of 1000342-66-4

CAS Number

1000342-66-4

IUPAC Name

3-iodo-4-methyl-1H-pyrrolo[3,2-c]pyridine

InChI

InChI=1S/C8H7IN2/c1-5-8-6(9)4-11-7(8)2-3-10-5/h2-4,11H,1H3

InChIKey

AUDKTNCLJDKEJL-UHFFFAOYSA-N

Canonical SMILES

CC1=NC=CC2=C1C(=CN2)I

Physical and chemical properties of 1000342-66-4

Boiling Point

370.8±37.0 °C at 760 mmHg

Density

1.9±0.1 g/cm3

Exact Mass

257.965393

Flash Point

178.0±26.5 °C

Index of Refraction

1.750

LogP

2.14

Molecular Formula

C8H7IN2

Molecular Weight

258.059

PSA

28.68000

Storage condition

2-8°C

Vapour Pressure

0.0±0.8 mmHg at 25°C

Applications of 1000342-66-4

The unique structure of 3-Iodo-4-methyl-1H-pyrrolo[3,2-c]pyridine allows it to interact effectively with various biological targets, making it valuable in drug discovery efforts. Its potential applications include:

  • Medicinal Chemistry: As a scaffold for developing new therapeutic agents targeting kinases.
  • Chemical Biology: As a tool compound for studying biological pathways involving specific kinases.
  • Material Science: Potential use in developing novel materials due to its unique electronic properties.

Interaction Studies of 1000342-66-4

Studies involving interaction profiles of 3-Iodo-4-methyl-1H-pyrrolo[3,2-c]pyridine have indicated its ability to bind to proteins involved in signal transduction pathways. For instance, derivatives have shown interactions with FMS kinase and other relevant targets, highlighting their potential as effective inhibitors in therapeutic contexts. This binding capability is essential for understanding the compound's mechanism of action and optimizing its pharmacological properties.

Biological Activity of 1000342-66-4

Research indicates that derivatives of 3-Iodo-4-methyl-1H-pyrrolo[3,2-c]pyridine exhibit significant biological activity. Notably, compounds within this class have shown promising results as inhibitors of specific kinases involved in cancer and inflammatory diseases. For example, certain derivatives demonstrate inhibitory effects against FMS kinase, suggesting potential applications in anticancer therapies. Additionally, some compounds have displayed antiviral properties with low cytotoxicity against VERO cells, indicating their suitability for further pharmacological exploration.