structure of 1-(5-amino-7-bromoindol-1-yl)ethanone

1-(5-amino-7-bromoindol-1-yl)ethanone

CAS No.: 1000343-32-7
M. Wt: 253.095
M. Fa: C10H9BrN2O
InChI Key: -

Names and Identifiers of 1-(5-amino-7-bromoindol-1-yl)ethanone

CAS Number

1000343-32-7

IUPAC Name

1-(5-azanyl-7-bromanyl-indol-1-yl)ethanone

Canonical SMILES

CC(=O)N1C=CC2=CC(=CC(=C21)Br)N

Physical and chemical properties of 1-(5-amino-7-bromoindol-1-yl)ethanone

Boiling Point

393.6±22.0 °C at 760 mmHg

Density

1.7±0.1 g/cm3

Exact Mass

251.989822

Flash Point

191.9±22.3 °C

Index of Refraction

1.677

LogP

2.06

Molecular Formula

C10H9BrN2O

Molecular Weight

253.095

PSA

48.02000

Vapour Pressure

0.0±0.9 mmHg at 25°C

Applications of 1-(5-amino-7-bromoindol-1-yl)ethanone

1-(5-Amino-7-bromo-1H-indol-1-yl)ethanone has potential applications in various fields:

  • Pharmaceutical Development: Due to its biological activities, it may serve as a lead compound for developing new anticancer or antimicrobial agents.
  • Research Tool: This compound can be used in biochemical assays to study enzyme interactions and cellular pathways involving indole derivatives.

Interaction Studies of 1-(5-amino-7-bromoindol-1-yl)ethanone

Interaction studies reveal that 1-(5-Amino-7-bromo-1H-indol-1-yl)ethanone may interact with various biomolecules:

  • Enzyme Inhibition: The compound has been shown to inhibit specific enzymes involved in cancer metabolism, suggesting its role as a therapeutic agent.
  • Receptor Binding: Preliminary studies indicate potential binding affinity to certain receptors associated with cancer progression and inflammation.

Biological Activity of 1-(5-amino-7-bromoindol-1-yl)ethanone

The biological activity of 1-(5-Amino-7-bromo-1H-indol-1-yl)ethanone is notable, particularly among indole derivatives. These compounds are known for their diverse pharmacological properties, including:

  • Anticancer Activity: Indole derivatives have been shown to inhibit cancer cell proliferation through various mechanisms, including apoptosis induction and cell cycle arrest.
  • Antimicrobial Properties: Some studies indicate that this compound may exhibit antimicrobial activity against certain bacterial strains.
  • Anti-inflammatory Effects: Indole derivatives often show potential in reducing inflammation, making them candidates for treating inflammatory diseases.