(4,5-Dimethylthiazol-2-YL)methanol
Names and Identifiers of (4,5-Dimethylthiazol-2-YL)methanol
CAS Number |
99839-16-4 |
|---|---|
EC Number |
845-226-8 |
MDL Number |
MFCD12198452 |
IUPAC Name |
(4,5-dimethyl-1,3-thiazol-2-yl)methanol |
InChI |
InChI=1S/C6H9NOS/c1-4-5(2)9-6(3-8)7-4/h8H,3H2,1-2H3 |
InChIKey |
NNZZUYMCPDVPQA-UHFFFAOYSA-N |
Canonical SMILES |
CC1=C(SC(=N1)CO)C |
UNSPSC Code |
12352100 |
Physical and chemical properties of (4,5-Dimethylthiazol-2-YL)methanol
Acidity coefficient |
13.07±0.10(Predicted) |
|---|---|
Boiling Point |
245.2±28.0 °C at 760 mmHg |
Density |
1.2±0.1 g/cm3 |
Exact Mass |
143.040482 |
Flash Point |
102.1±24.0 °C |
Index of Refraction |
1.569 |
LogP |
1.23 |
Melting Point |
44-45 °C |
Molecular Formula |
C6H9NOS |
Molecular Weight |
143.207 |
PSA |
61.36000 |
Storage condition |
2-8°C |
Vapour Pressure |
0.0±0.5 mmHg at 25°C |
Safety Information of (4,5-Dimethylthiazol-2-YL)methanol
Applications of (4,5-Dimethylthiazol-2-YL)methanol
(4,5-Dimethylthiazol-2-YL)methanol finds applications in:
- Cell Viability Assays: Used extensively in cytotoxicity testing and drug screening.
- Biochemical Research: Serves as a reagent in various biochemical assays due to its ability to indicate metabolic activity.
- Pharmaceutical Development: Potential precursor for developing new therapeutic agents targeting specific biological pathways.
Interaction Studies of (4,5-Dimethylthiazol-2-YL)methanol
Studies involving (4,5-Dimethylthiazol-2-YL)methanol often focus on its interactions with other compounds in biological systems. Notable interactions include:
- Cellular Metabolism: It interacts with mitochondrial enzymes during the MTT assay, influencing the accuracy of viability results.
- Drug Interactions: Research into how this compound affects or is affected by other drugs can provide insights into its potential therapeutic uses.
These interactions are crucial for understanding the compound's behavior in biological systems.
Biological Activity of (4,5-Dimethylthiazol-2-YL)methanol
(4,5-Dimethylthiazol-2-YL)methanol exhibits biological activities that are of interest in pharmacology. Notably, it is involved in the MTT assay, a widely used method for assessing cell viability. This assay relies on the reduction of the MTT compound by metabolically active cells to form a colored formazan product, which can be quantified spectrophotometrically. The biological activity of this compound is linked to its ability to serve as an indicator of cellular metabolic activity.
Physical sample testing spectrum (NMR) of (4,5-Dimethylthiazol-2-YL)methanol
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